卟啉类化合物在仿生化学中可以作为模拟叶绿素、血红素、维生素B_12等天然产物的模型化合物母体,其有关研究日益增多,颇为人们所重视。1964年,Adler就提出了合成四苯基卟啉(简称TppH_2)的反应机理;直到1967年他提出的方法才基本上解决了此类化合物的合成问题(产率20％左右),至今一直被人们采用。1987年,Lindsey等人提出了一种产率较高的合成方法,但反应步骤多、条件 Porphyrins can be used as the parent of model compounds that simulate natural products such as chlorophyll, heme, and vitamin B_12 in biomimetic chemistry, and their related researches are increasing day by day. In 1964, Adler proposed the reaction mechanism of synthesizing tetraphenylporphyrin (abbreviated as TppH_2). Until 1967, his method basically solved the problem of synthesis of such compounds (about 20% yield) and has been People use it. In 1987, Lindsey et al proposed a higher yield of synthetic methods, but the reaction steps, conditions