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作者报道用家兔作试验考察前列腺素E_2及F_(2α)的事后避孕作用。肌注;母兔交配后24小时,皮下注射3毫克/公斤的药物,14天后处死,记录黄体数、着床数、存活及退化胚胎数。5只注射PGE_2的母兔,有18个存活胚胎。根据观察到的黄体数汁算。有25%的卵未着床,11%的胚胎退化。6只注射PGF_(2α)的母兔,有8个存活胚胎,61%的卵未着床,17%的胚胎退化。5只对照母免有29个着床,12%的卵本着床。静注:母兔支配后4天静注2毫克/公斤剂量
The authors report the use of rabbits as a test to examine the prospective contraceptive effects of prostaglandin E_2 and F_ (2α). Intramuscular injection; female rabbits 24 hours after mating, subcutaneous injection of 3 mg / kg of drug, 14 days after the death, recording luteal number, implantation, survival and the number of degraded embryos. Five females injected with PGE_2 had 18 surviving embryos. According to the observed number of luteal count. 25% of the eggs are not implanted and 11% of the embryos degenerate. Six females injected with PGF_ (2α) had 8 surviving embryos, 61% had no implantation and 17% had embryo degeneration. There were 29 implants in the 5 control mothers and 12% of the eggs in the implants. Intravenous injection: intravenous injection of 2 mg / kg dose 4 days after dosing of female rabbits