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目的探讨突发性耳聋(以下称突聋)预后相关因素对患者听力恢复的影响及回顾凯时(前列腺素E1)治疗突聋的疗效。方法对114例突聋患者治疗前后进行纯音听力测试，治疗药物标准为：静脉推注凯时2ml，1次/d,口服醋酸地塞米松1.5mg，3次/d,达纳康(银杏叶片)40mg，3次/d，怡神保(甲钴胺片)：0.5mg，3次/d，共7d；分析年龄、性别、听力损失程度、就诊时间、伴随症状对预后的影响及治疗的总有效率和平均听阈改善情况。结果就诊时间、耳鸣、年龄、听力损失程度是突聋预后的相关因素,凯时治疗突聋的总有效率60.5豫。结论就诊时间和耳鸣与突聋预后呈正相关，年龄和听力损失程度与突聋预后呈负相关,平均听力损失≤40dB HL者,预后更好。“,”Objective To investigate prognostic factors and review therapeutic ef ect of lipoprostaglandinE1,on sudden sensorineural hearing loss. Methods One hundred and fourteen patients have pure tone test before and after the therapy, the standard treatment is:intravenous injection kaishi 2ml per day、dexamethasone 1.5mg ,Tanakan 40mg three times a day and Mecobalamin Tablets 0.5mg three times a day oral y for seven days. Results Initial visit after onset of the hearing loss、tinnitus,age,the severity of hearing loss are the prognostic factors. The overal recovery of lipoprostaglandinE1 is 60.5%. Conclusion Initial visit after onset of the hearing loss and tinnitus are in positive cor elation, while age and the severity of hearing loss are in negative correlation. Hearing loss of 40dB HL or less has a bet er prognosis.