应用毛细管柱(DB-1)气相色谱法,对临床上具有重要诊断价值意义的59种标准有机酸的亚甲基单位值(MU)进行了测算,并与填充柱(5％OV-1、4％OV-17)进行了比较,且通过毛细管柱气相色谱法对正常和异常儿童尿液有机酸进行了分析。结果显示:毛细管柱气相色谱法的准确性和可靠性高,稳定性和重复性好,优于填充柱,作者认为:该法可作为国内有机酸尿症化学诊断的主要手段。 Methylene units (MU) of 59 standard organic acids with clinically significant diagnostic value were calculated by capillary gas chromatography (DB-1) and were compared with packed column (5% OV-1, 4% OV-17) were compared, and normal and abnormal urine organic acids were analyzed by capillary gas chromatography. The results show that capillary gas chromatography has the advantages of high accuracy and reliability, good stability and repeatability, and superior to packed columns. The author believes that this method can be used as the main method of chemical diagnosis of organic aciduria in China.