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耐甲氧西林金黄色葡萄球菌 (methicillin -resistantstaphylococcusaureus ,MRSA )是目前引起医源性感染的主要病菌之一 ,对多种抗生素耐药 ,致病力强且治疗效果差。自 1961年发现第一株MRSA以来 ,由于大量抗生素的作用 ,世界各地临床分离MRSA阳性率越来越高 ,耐药程度日益加重 ,目前已成为世界医学界关注的热点。本文就MRSA的流行情况、流行的相关因素、耐药机制、检测技术及其预防和临床药物治疗进展进行了综述
Methicillin-resistant staphylococcus aureus (MRSA) is one of the major pathogens causing iatrogenic infection. It is resistant to many antibiotics and has strong pathogenicity and poor therapeutic effect. Since the first strain of MRSA was discovered in 1961, the positive rate of clinical isolates of MRSA in various parts of the world is getting higher and higher due to the effect of a large number of antibiotics, and the drug resistance is getting more and more serious. At present, it has become a hot spot in the medical world. This article reviews the prevalence of MRSA, the prevalence of related factors, drug resistance mechanisms, detection techniques and the progress of prevention and clinical drug treatment