脓毒症是临床危重症患者的主要死因之一,越来越多的研究显示,他汀类药物可降低脓毒症患者的病死率,其中主要机制之一可能与保护血管内皮细胞功能有关。本文就他汀类药物对脓毒症血管内皮细胞功能的影响作一综述。 Sepsis is one of the major causes of death in critically ill patients. More and more studies have shown that statins can reduce the mortality of patients with sepsis. One of the major mechanisms may be related to the protection of vascular endothelial function. This article reviews the effects of statins on the function of vascular endothelial cells in sepsis.