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乳腺癌的化学药物治疗(简称化疗)开始于40年代初,多为晚期病人的单药治疗,1966年GreenSpan初倡晚期乳腺癌的联合化疗以来~1,其发展迅速。目前国内临床试用的化疗药物有30余种,其中10余种对乳腺癌有明显疗效。单一药物可取得20～40％的有效率,3～5种药物同时联合化疗可将有效率提高到50～80％以上,且完全缓解率可达20％,个别病人可生存10年以上,但化疗对晚期乳腺癌仍属姑息治疗范畴。本文总结我科在1973～1983年间治疗的86例晚期乳腺癌。
Chemotherapeutic treatment of breast cancer (chemotherapy) began in the early 40’s and was mostly monotherapy for advanced patients. Since GreenSpan began initial chemotherapy for advanced breast cancer in 1966, it has developed rapidly. At present, there are more than 30 kinds of chemotherapeutic drugs that have been clinically tested in clinics, of which more than 10 have significant effects on breast cancer. A single drug can achieve an effective rate of 20 to 40%, and 3 to 5 drugs can simultaneously increase the effective rate to 50 to 80%, and the complete remission rate can reach 20%. Individual patients can survive for more than 10 years, but Chemotherapy is still a palliative treatment for advanced breast cancer. This article summarizes 86 cases of advanced breast cancer treated in our department between 1973 and 1983.