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目的探讨血栓抽吸联合冠脉内注射替罗非班和硝酸甘油在急诊PCI中的作用。方法 2015年3月~2016年12月我院STEMI急诊PCI人群,按患者入院顺序分为治疗组和对照组,提取两组TIMI3级血流例数、cTFC、CK-M峰值、达峰时间、血压变化、左室EF值、左室舒张末内径等资料,采用x~2检验及t检验。结果两组TIMI3级血流例数及cTFC比较,两组心肌标志物比较,两组术后心脏超声指标变化情况,左室EF值及左室舒张末内径,治疗组均优于对照组;两组治疗前后血压比较,治疗组无明显变化,对照组在注药前后血压变化差异有统计学意义。结论经抽吸导管注射替罗非班和硝酸甘油,可以增加TIMI3级血流例数,安全性更高,操作简单,不增加患者费用,可应用于临床。
Objective To investigate the effect of thrombus aspiration combined with intracoronary injection of tirofiban and nitroglycerin in emergency PCI. Methods From March 2015 to December 2016, the STEMI emergency PCI population in our hospital was divided into treatment group and control group according to the patient admission order. Two groups of TIMI grade 3 blood flow number, cTFC, CK-M peak, peak time, Blood pressure changes, left ventricular EF value, left ventricular end diastolic diameter and other data, using x ~ 2 test and t test. Results The TIMI grade 3 blood flow number and cTFC were compared between the two groups. The change of echocardiographic parameters, left ventricular EF and left ventricular end-diastolic diameter of the two groups were better than those of the control group Blood pressure before and after treatment in the treatment group did not change significantly in the control group before and after injection of blood pressure was statistically significant differences. Conclusion Intrathecal injection of tirofiban and nitroglycerin can increase the number of cases of TIMI grade 3 blood flow, with higher safety, simple operation and no increase in patients’ costs, which can be applied to clinic.