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ACTH的测定并不容易。直到敏感的和比较特异的放射免疫测定出现以来,才常规地应用。本文介绍用此法测定ACTH的临床经验。作者检查了50例年龄为20～45岁的健康人在上午9时的血浆ACTH,结果为5～95微微克/毫升,6例在午夜抽取标本,其范围为0～35微微克/毫升。20例皮质醇增多症的病人,其中8例无论是在上午9时或午夜的血标本中均未检出ACTH,被诊断为肾上腺皮质醇增多症,手术证实为肾上腺肿瘤,并成功地作了摘除,其中5例组织学上是恶性的。其余12个病
ACTH determination is not easy. Until the sensitive and more specific radioimmunoassay appeared, it is routinely applied. This article describes the use of this method to determine the clinical experience of ACTH. The authors examined plasma ACTH levels in 50 healthy people aged 20-45 years at 9am and found 5-95 pg / mL. Six of them took samples at midnight, ranging from 0 to 35 pg / mL. Of the 20 patients with Cushing’s disease, 8 had no ACTH detected in blood samples at 9am or midnight, were diagnosed with adrenocortisolism, had surgery confirmed as adrenal tumors, and were successfully treated 5 cases were histologically malignant. The remaining 12 diseases