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作者探讨了烹调油烟（ Ｃ Ｏ Ｆ）对雄性大鼠生殖性损伤的毒作用机制。按时相（２０、４０、６０天）给雄性 Ｓ Ｄ 大鼠吸入同一浓度（３６～５３ ｍ ｇ／ｍ ３ ）的 Ｃ Ｏ Ｆ，观察 Ｃ Ｏ Ｆ对睾丸及其微量元素的影响。结果表明，吸入 Ｃ Ｏ Ｆ４０、６０天时大鼠体重均有降低趋势；睾丸、附睾脏器及其与体重的比值均分别低于对照组（ Ｐ＜ ００５），且呈时效关系；染毒４０、６０天时精子含量和存活率显著降低，而畸形率明显增高，且死精子多；染毒４０、６０天时睾丸中 Ｚｎ、 Ｍｎ 代谢紊乱，出现 Ｚｎ 低， Ｍｎ 高，均呈时效关系。提示， Ｃ Ｏ Ｆ对性腺具有明显毒性，同时微量元素代谢紊乱可能对性腺的损害起了重要作用。
The authors explored the toxic effects of cooking fumes (C O F) on reproductive injury in male rats. Male SD rats were inhaled with the same concentration of C O F (36-53 m g / m 3) on the time phase (20, 40 and 60 days) to observe the effect of CO on the testis and its trace elements. The results showed that the body weight of rats in C O F40 group decreased on the 60th and 60th day. The ratio of testis and epididymis to body weight were lower than that of the control group (P <005) 40 and 60 days after exposure, the sperm content and survival rate decreased significantly, while the deformity rate increased significantly, and the number of dead sperm increased. At 40 and 60 days, the metabolism of Zn and Mn in the testes was disturbed, with Zn low and Mn high, Effective relationship. Tip, C O F on gonads has obvious toxicity, while metabolic disorders of trace elements may play an important role in the damage of the gonads.