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砷性皮肤角化,特别在掌蹠的疣状角化通常认为是慢性砷中毒的特征,同时它也被反复强调为砷癌的先兆。我们在华北七所孙世荃主任的技术指导和药物支持下,对1979年“个旧市砷污染对市民的远期危害的初步调查”中发现的及门诊、住院皮肤癌、肺癌伴皮肤角化患者共32例进行了维甲酸(以下简称RA)治疗观察,现将情况报告如下:
Arsenic skin keratosis, particularly verruca parakeratosis, is often characterized as chronic arsenic poisoning and is also repeatedly highlighted as a precursor of arsenic cancer. Under the technical guidance and drug support of the director of Dr. Sun Shizuen of the seven hospitals in North China, we found out in a preliminary investigation of the “long-term harm of citizens to arsenic caused by arsenic pollution in Gejiu City in 1979” and outpatients, hospitalized patients with skin cancer and lung cancer with skin keratosis 32 cases of retinoic acid (hereinafter referred to as RA) treatment, the situation is reported as follows: