盐酸苯达莫司汀作为新一代抗癌药物,对多种癌症具有明显的治疗作用。临床应用表明,本品单独治疗或联合用药治疗非霍奇金淋巴瘤、多发性骨髓瘤、慢性淋巴细胞白血病和乳腺癌等,疗效确切,明显降低复发率与死亡率,而且不良反应小,安全性高,值得推广应用。文中对其药理作用、临床研究及安全性进行综述。 Bendamustine hydrochloride as a new generation of anticancer drugs, has a significant therapeutic effect on a variety of cancers. Clinical application shows that this product alone or in combination therapy for non-Hodgkin’s lymphoma, multiple myeloma, chronic lymphocytic leukemia and breast cancer, the exact effect, significantly reduce the recurrence rate and mortality, and adverse reactions, safety High, it is worth promoting application. In this paper, its pharmacological effects, clinical studies and safety are reviewed.