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目的探讨多索茶碱对慢性阻塞性肺疾病(COPD)治疗的效果。方法选取在我院进行治疗的COPD患者300例,随机分成氨茶碱治疗组(对照组)与多索茶碱治疗组(观察组),在两组患者均口服氨茶碱0.2 g/d的情况下,对照组患者给予静脉滴注氨茶碱250 mg+5%葡萄糖注射液225 ml,观察组患者给予静脉滴注多索茶碱300 mg+5%葡萄糖注射液225 ml,治疗10 d后,观察两组患者的不良反应的发生率以及治疗康复情况。结果观察组患者总有效率为94.0%,明显高于对照组的74.7%(P<0.05);观察组患者的不良反应发生率为2.7%,明显低于对照组的9.3%(P<0.05)。结论多索茶碱对改善COPD的病症情况效果较好,且作用速度快,疗效安全可靠。
Objective To investigate the effect of doxofylline on chronic obstructive pulmonary disease (COPD). Methods 300 patients with COPD treated in our hospital were randomly divided into aminophylline treatment group (control group) and doxofylline treatment group (observation group). Patients in both groups were given aminophylline 0.2 g / d In the control group, patients in the control group received intravenous infusion of 225 mg of aminophylline 250 mg + 5% dextrose and 225 ml of doxofylline 300 mg + 5% glucose injection in the observation group. After 10 days of treatment, , Observed the incidence of adverse reactions in two groups of patients and the treatment of rehabilitation. Results The total effective rate in the observation group was 94.0%, significantly higher than 74.7% in the control group (P <0.05). The adverse reaction rate in the observation group was 2.7%, significantly lower than that in the control group (9.3%, P <0.05) . Conclusion Doxofylline is effective in improving the condition of COPD and its effect is fast and safe.