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目的探讨药物洗脱支架治疗后冠状动脉再狭窄与临床和造影的相关因素。方法入选416例冠状动脉造影(CAG)资料完整的冠心病患者,男性328例,女性88例,共置入支架470枚,按照CAG结果分为再狭窄组59例和无再狭窄组357例,平均造影随访时间(7．91±2．37)个月。结果再狭窄组CAG示61枚支架发生再狭窄(13．0％),女性、既往冠状动脉旁路移植术(CABG)病史、慢性闭塞(CTO)病变病史、最大球囊释放压力、置入支架长度与术后再狭窄相关(P<0．05);置入支架血管直径与再狭窄高度相关(OR=0．61,95％CI:0．43～0．82,P< 0．01)。结论女性、既往CABG病史、CTO病变、血管直径、置入支架长度是支架术后再狭窄的危险因素,而糖尿病史等与再狭窄无关。
Objective To investigate the factors related to clinical and angiographic coronary artery restenosis after drug-eluting stent treatment. Methods A total of 416 coronary artery disease patients with coronary angiography (CAG) were enrolled in this study. There were 328 males and 88 females. A total of 470 scaffolds were included. According to CAG results, there were 597 patients with restenosis group and 357 patients without restenosis group. The average contrast-induced follow-up time (7.91 ± 2.37) months. Results CAG of restenosis group showed restenosis (13.0%) in 61 stents, history of female coronary artery bypass grafting (CABG), history of chronic occlusion (CTO), maximum balloon release pressure, placement of stents The length of the stent was related to the restenosis after operation (P <0.05). The diameter of the stenting vessel was highly correlated with restenosis (OR = 0.61, 95% CI: 0.43-0.82, P <0.01) . CONCLUSIONS: Women, previous history of CABG, CTO lesions, vessel diameter, and stenting length were risk factors for restenosis after stenting, whereas history of diabetes mellitus and other factors did not correlate with restenosis.