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本文测定３２例青少年单纯性肥胖症的肾上腺皮质功能，结果显示：①２１例病人血浆总皮质醇（ｐｌａｓｍａｔｏｔａｌｃｏｒｔｉｓｏｌ，ＰＴＣ）昼夜节律存在不同程度、不同类型的异常；②尿游离皮质醇（ｕｒｉｎａｒｙｆｒｅｅｃｏｒｔｉｓｏｌ，ＵＦＣ）的含量在正常范围；③地塞米松抑制筛查试验正常。说明约６５．６％青少年单纯性肥胖症的肾上腺皮质功能活动水平较高，但对地塞米松的反馈抑制作用仍十分敏感，这与正常青少年及柯兴综合征患者均不同。
In this study, 32 cases of adolescent simple obesity adrenal function, the results showed: ① 21 patients with plasma total cortisol (plasmatotalcortisol, PTC) there are different degrees of circadian rhythm, different types of abnormalities; ② urinary free cortisol (urinaryfreecortisol, UFC) Content in the normal range; ③ dexamethasone suppression screening test was normal. This shows that about 65.6% of adolescents with simple obesity have higher levels of adrenocortical functional activity, but the feedback inhibition of dexamethasone is still very sensitive, which is different from normal adolescents and Cushing’s syndrome patients.