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目的 :探讨北海地区幽门螺杆菌 (HerlicobacterPylori,HP)感染与上消化道疾病关系 ,为防治本病提供参考。方法 :1 0 50例门诊病房具有上消化症状患者 ,行胃镜检查、胃镜下取活检作胃粘膜组织切片检查及快速尿素酶试验检测HP的感染率 ,并分析与职业 ,上消化疼痛的关系。结果 :HP总检出率 52 .9% ,男、女性别HP感染无差异 ,分别为 53 .8%、51 .1 %。年龄以 30～ 59岁感染率最高 (57.1 % ) ,1 6～ 2 9岁较低 (38.5 % ) ,职业以渔民感染率最高 (76 .8% ) ,农民次之 (65 .1 % ) ;上消化道疾病HP感染 ,以球部溃疡最高 (64 .9% ) ,糜烂性胃炎次之 (60 .4% ) ,萎缩性胃炎最低 (2 5 % )。结论 :本地区HP感染率以渔民、农民高为特点 ,HP感染是本地区消化性溃疡、慢性胃炎的主要致病因素之一
Objective: To investigate the relationship between Helicobacter pylori (HP) infection and upper gastrointestinal diseases in the North Sea region and to provide references for the prevention and treatment of this disease. Methods: One hundred and fifty patients with upper gastrointestinal symptoms were enrolled in the outpatient ward. Gastroscopy, endoscopy under gastroscopy were performed for gastric mucosa biopsy and rapid urease test to detect the infection rate of HP, and to analyze the relationship with occupational and upper digestive pain. Results: The overall detection rate of HP was 52.9%. No difference was found between male and female HP infection, which was 53.8% and 51.1% respectively. The highest infection rate (57.1%) was in the age group of 30-59 years, the lower was 38.5% in the age group of 16-29 years (76.8%) and the second was farmer (65.1%). HP infection of upper gastrointestinal diseases, the highest ulcer (64.9%), erosive gastritis (60.4%), the lowest atrophy gastritis (25%). Conclusion: The prevalence of HP infection in this area is characterized by fishermen and peasants. HP infection is one of the main causative factors of peptic ulcer and chronic gastritis in this area