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目的:通过比较来探讨慢性肾脏病患者与健康成人之间生存质量的差异。方法:应用慢性肾脏病特异性生存质量量表(KDQOLTM-36)对110例慢性肾脏病1～4期患者以及70例健康成人进行生存质量评估,观察比较两组人群生存质量各维度的评分情况。结果:慢性肾脏病患者组与健康成人组在症状影响、肾病影响、肾病负担、疼痛度、身体功能、社会功能、精力体力、情感状况等8个方面比较,差异均有统计学意义(P<0.01)。慢性肾脏病患者组所有负向计分项目高于健康成人组(P<0.05),而正向计分项目低于健康成人组(P<0.01)。结论:慢性肾脏病患者在生存质量各方面都明显较健康成人下降。
Aims: To compare the quality of life between patients with chronic kidney disease and healthy adults. Methods: The quality of life of 110 chronic kidney disease patients with stage 1 ~ 4 and 70 healthy adults were evaluated by KDQOL-36. The scores of quality of life in each group were compared . Results: There were significant differences in 8 aspects of symptom, kidney disease, burden of kidney disease, pain, physical function, social function, energy and physical strength, emotional status among patients with chronic kidney disease and healthy adults (P < 0.01). All patients with chronic kidney disease had higher negative scores than healthy adults (P <0.05), while those with positive scores were lower than healthy adults (P <0.01). CONCLUSIONS: Patients with chronic kidney disease have significantly decreased in all aspects of quality of life compared to healthy adults.