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目的:探讨超选择性子宫动脉灌注化疗栓塞术治疗妊娠滋养细胞肿瘤的疗效。方法:回顾性分析2004年1月～2006年1月在江西省妇幼保健院接受介入治疗的26例妊娠滋养细胞肿瘤患者的资料。对全部研究对象行超选择性子宫动脉灌注化疗栓塞术,采用EMA-CO化疗方案,术中行灌注化疗后采用明胶海绵颗粒动脉栓塞,介入治疗后联合静脉化疗。结果:26例患者中17例完全缓解(65.39%),7例部分缓解(26.92%),2例无效(7.69%),总有效率为92.3%。随访时间12～42个月不等,近期疗效满意,其中3例带瘤生存,无一例复发。结论:超选择性子宫动脉灌注化疗栓塞术治疗妊娠滋养细胞肿瘤,疗效确切,值得推广应用。
Objective: To investigate the effect of superselective uterine arterial chemoembolization on gestational trophoblastic tumor. Methods: The data of 26 cases of gestational trophoblastic tumor who underwent interventional treatment in MCH from January 2004 to January 2006 were retrospectively analyzed. All patients underwent superselective uterine arterial chemoembolization with EMA-CO chemotherapy. Intraperitoneal chemotherapy followed by gelatin sponge particle embolization followed by interventional chemotherapy followed by intravenous chemotherapy. Results: Of the 26 patients, 17 were completely relieved (65.39%), 7 were partially relieved (26.92%), 2 were ineffective (7.69%) and the total effective rate was 92.3%. Follow-up time ranging from 12 to 42 months, the recent satisfactory results, including 3 cases of tumor survival, no case of recurrence. Conclusion: Superselective uterine arterial chemoembolization in treatment of gestational trophoblastic tumor is effective and worthy of promotion.