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目的探讨咽旁间隙肿瘤的诊断和治疗。方法回顾性分析研究45例咽旁间隙肿瘤的临床表现、病理类型及诊治方法。结果45例咽旁间隙肿瘤肿良性36例(占80%)、恶性9例(占20%),神经源性良性肿瘤(16例)及涎腺混合瘤(11例)是最常见的肿瘤。临床表现为颈部或咽侧的肿块,可伴有吞咽不适、咽痛、头面麻木、听力下降、颈交感神经麻痹综合征(Horner syndrome)等症状。CT或MRI能显示肿瘤大小、形态、位置、与周围结构的关系等。本组肿瘤均经颈外侧切口入路手术切除。恶性肿瘤术后加用了放、化疗。随访1~10年,良性肿瘤无复发,恶性肿瘤3年生存率44%,5年生存率33%。结论CT、MRI对咽旁间隙肿瘤的诊断及指导手术有重要意义。颈外侧切口径路切除咽旁间隙肿瘤简易、安全、有效。
Objective To explore the diagnosis and treatment of parapharyngeal space tumor. Methods Retrospective analysis of 45 cases of parapharyngeal space tumor clinical manifestations, pathological types and diagnosis and treatment methods. Results 45 cases of parapharyngeal space tumor were benign, 36 cases were malignant (80%), 9 were malignant (20%), benign neurogenic tumors (16 cases) and salivary gland mixed tumors (11 cases) were the most common tumors. Clinical manifestations of the neck or pharyngeal mass, may be accompanied by swallowing discomfort, sore throat, head numbness, hearing loss, cervical sympathetic syndrome (Horner syndrome) and other symptoms. CT or MRI can show tumor size, shape, location, and the relationship between the surrounding structure. The group of tumors were surgically resected through the external neck incision. After surgery with malignant tumor put radiotherapy and chemotherapy. Follow-up 1 to 10 years, no recurrence of benign tumors, 3-year survival rate of 44% of malignant tumors, 5-year survival rate of 33%. Conclusion CT and MRI are important for the diagnosis and guidance of parapharyngeal space tumors. Excision of parapharyngeal space tumor by lateral neck incision is simple, safe and effective.