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利用容积扫描和首过时间技术前瞻性了解胃癌灌注的CT表现特征。35例胃癌患者的CT灌注数据与24例正常胃进行了比较。四个灌注参数:灌注值(PF)、峰值强度(PE)、峰值时间(TTP)和血容量(BV)在对照组和病例组之间,及发生了淋巴结转移和未发生淋巴结转移组之间进行了比较,对比较中有差异的参数进行ROC分析以确定胃癌和正常胃灌注参数的临界值。结果发现只有血容量这一参数在病例组和对照组之间有显著性差异。BV为8.6 ml.100g-1确定为区分胃癌和正常胃的临界值。所有灌注参数在胃癌有和无淋巴结转移的亚组之间没有显著性差异。因此利用容积扫描和首过时间技术进行胃癌全肿瘤灌注能够了解肿瘤血管情况,有助于胃癌的诊断。
Prospective assessment of CT features of gastric perfusion using volume scanning and first-pass techniques. CT perfusion data from 35 patients with gastric cancer were compared with 24 normal stomachs. Four perfusion parameters: perfusion value (PF), peak intensity (PE), peak time (TTP) and blood volume (BV) between the control group and the case group, and between lymph node metastasis and non-occurrence of lymph node metastasis group Were compared and ROC analysis was performed on the differences in the parameters to determine the cut-off values for gastric cancer and normal gastric perfusion parameters. The results showed that only the blood volume of this parameter in the case group and the control group were significantly different. The BV of 8.6 ml.100 g-1 was established as a cut-off value for distinguishing gastric cancer from normal stomach. All perfusion parameters did not differ significantly between subgroups with and without lymph node metastasis. Therefore, the use of volume scanning and first-pass technology for gastric cancer perfusion can understand tumor blood vessels, contribute to the diagnosis of gastric cancer.