背景和目的 使用双氯高灭酸可引起药物依赖性抗体和/或自身抗体,从而导致免疫溶血性贫血症(IHA),口服或肌肉注射药物的相关性仍未可知,本文报道1例耐受口服双氯高灭酸的病人在肌注这种药物后发展为严重的IHA。病人和方法1例66岁的妇女因黄疸和呕吐人院,其最初被推测为胆囊切除后综合征,不久发展为溶血和肾衰竭,尽管症状和征兆提示为 BACKGROUND & OBJECTIVE The use of diclofenac to cause drug-dependent and / or autoantibodies leading to immune-hemolytic anemia (IHA), the relevance of which is orally or intramuscularly still unknown, is reported in this article in 1 patient Patients with oral diclofenac develop severe IHA after intramuscular injection of this drug. PATIENTS AND METHODS A 66-year-old woman hospitalized for jaundice and vomiting was originally hypothesized to be a cholecystectomy syndrome, which soon developed to hemolysis and renal failure despite the presence of symptoms and signs suggesting