论文部分内容阅读
本文对我院1987年12月至1989年11月间进行的9例HLA相合的异基因骨髓移植供受者的植入情况做了分析。我们采用了国际骨髓移植登记处的移植成功指标,及常规的细胞遗传学检查,结果全部患者均有间接的临床植入证据,其中5例有直接的细胞遗传学证据。本文综合文献提示,细胞遗传学分析在移植证明中具有很重要的意义,但其缺陷也是显而易见的。DNA-RFLP的检测可弥补常规方法的缺陷,并获得准确可靠的植入依据。
In this paper, our hospital from December 1987 to November 1989 carried out in 9 cases of HLA-matched allogeneic bone marrow transplantation donor recipients were analyzed. We used the International Bone Marrow Transplant Registry transplant success indicators, and conventional cytogenetic examination, the results of all patients with indirect clinical evidence of implantation, of which 5 cases have direct cytogenetic evidence. This article suggests that the literature, cytogenetic analysis in the transplant proved to be of great significance, but its shortcomings are also obvious. DNA-RFLP detection can make up for the shortcomings of conventional methods, and obtain accurate and reliable basis for implantation.