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目的分析鼻内镜下视神经减压术在外伤性视神经病患者中的应用效果。方法选取2014年1月至2016年1月我院收治的外伤性视神经病患者100例(100眼)为观察对象,按治疗方法不同分为观察组与对照组,每组各50例。对照组采取药物治疗模式,观察组在对照组的基础上,待病情稳定后采取鼻内镜下视神经减压术治疗。术后至少随访1 a,对比两组患者的临床疗效、视力、视觉诱发电位检查结果、不良反应发生率等。结果观察组与对照组的治疗有效率分别为76.0%和36.0%,两组相比差异有统计学意义(P<0.05)。观察组22眼无光感者中16眼视力提高,13眼光感者中9眼视力提高,11眼眼前手动者中9眼视力提高,4眼眼前数指者视力全部提高;对照组20眼无光感者中6眼视力提高,14眼光感者中6眼视力提高,12眼眼前手动者中5眼视力提高,4眼眼前数指者中1眼视力提高。治疗后,观察组P100潜伏期为(116.85±7.96)ms,P100振幅为(5.11±1.16)μV,均优于对照组的(105.62±6.82)ms、(4.31±1.25)μV。观察组不良反应发生率显著低于对照组(P=0.000)。结论鼻内镜下视神经减压术在外伤性视神经病患者中具有较好的应用效果和安全性,能够有效改善患者的视力,有助于提升患者的生活质量,值得在临床中推广使用。
Objective To analyze the effect of endoscopic optic nerve decompression in patients with traumatic optic neuropathy. Methods 100 patients (100 eyes) with traumatic optic neuropathy admitted in our hospital from January 2014 to January 2016 were selected as the observation group and divided into observation group and control group according to different treatment methods, with 50 cases in each group. Control group to take medication model, the observation group on the basis of the control group, to be stable after taking endoscopic optic nerve decompression treatment. After at least 1 year of follow-up, the clinical efficacy, visual acuity, visual evoked potential test results, incidence of adverse reactions and so on were compared between the two groups. Results The effective rates of observation group and control group were 76.0% and 36.0% respectively, there was significant difference between the two groups (P <0.05). The visual acuity of 16 eyes of 22 eyes of the observation group was improved, 9 eyes of 13 eyes of light perception were improved, 9 eyes of 11 eyes before eyesight were improved, 4 eyes before eyes were all improved, while 20 eyes of the control group had no eyes Light perception in 6 eyes improved visual acuity in 6 eyes of 14 light perception, visual acuity improved in 5 eyes of 12 eyes in front of hand, 4 eyes in one of the fingers increased visual acuity. After treatment, the latency of P100 in the observation group was (116.85 ± 7.96) ms and the amplitude of P100 was (5.11 ± 1.16) μV, both of which were superior to those of the control group (105.62 ± 6.82) ms and (4.31 ± 1.25) μV. The incidence of adverse reactions in the observation group was significantly lower than that in the control group (P = 0.000). Conclusions Endoscopic decompression of optic nerve has good application and safety in patients with traumatic optic neuropathy, which can effectively improve the vision of patients and improve the quality of life of patients, which is worth popularizing in clinical practice.