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文献中常将嗜碘性甲状腺肿(Iodine-avid goitre)与地方性甲状腺肿混为一谈。后者一贯被认为与缺碘有很大的关系,但尚未发现明确的生化异常,腺体中并无大量储存未被利用的无机碘,没有甲状腺素的合成障碍,甲状腺蛋自正常,也不存在抗甲状腺抗体。而非毒性嗜碘性甲状腺肿不总是地方病,临床上不多见,认识这种情况对于避免发生不必要的手术并发症具有重要的意义。作者于1970~1987年期间所施行的1580例非毒性多发性结节性甲状腺肿中,有17例符合所规定的嗜碘性甲状腺肿诊断标准,即(1)临床上表现为非毒
Iodine-avid goitre is often confused with endemic goitre in the literature. The latter has long been recognized as having a strong association with iodine deficiency but no clear biochemical abnormalities have yet been identified. There is no significant accumulation of unused inorganic iodine in the glands, synthetic barriers to thyroid hormone, thyroid eggs are normal, nor Anti-thyroid antibodies exist. Non-toxic iodinated goiter is not always endemic and rare in clinic, and understanding this situation is of great significance in avoiding unnecessary surgical complications. Of the 1580 non-toxic nodular goiter cases administered by the authors between 1970 and 1987, 17 met the criteria for the diagnosis of idiopathic goiter, namely (1) clinically non-toxic