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本文就近１５年来作者对广州地区糖尿病的患病率及其相关因素、诊断标准、致病性及其死亡原因、发病机理、胰岛β细胞功能与糖尿病分型、血管病变发病机理、饮食治疗、第２代磺脲类降糖药的临床应用与作用机理、病情监测等一系列研究作一扼要的综述，反映了作者对这些问题的了解和认识，提出见解，其中不少具有自己的特色，特别是在大血管病变和微血管病变发病机理，以及第２代磺脲类降糖药的临床应用与作用机理等方面。这些结果为今后对糖尿病防治的研究进一步打下基础，具有理论意义和实用价值。
This article in the past 15 years, the author of the prevalence of diabetes in Guangzhou and its related factors, diagnostic criteria, pathogenicity and its causes of death, pathogenesis, pancreatic β-cell function and type of diabetes, pathogenesis of vascular disease, diet, The second generation of sulfonylurea hypoglycemic agents clinical application and mechanism of action, disease monitoring and a series of studies for a brief overview, reflecting the author of these issues understanding and understanding, put forward opinions, many of which have their own characteristics, especially Is in the pathogenesis of macrovascular disease and microangiopathy, as well as the second generation of sulfonylurea clinical application and mechanism of action and so on. These results lay a foundation for further research on the prevention and treatment of diabetes in the future, which has theoretical significance and practical value.