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本实验对窒息大鼠软脑膜微循环改变和复方丹参及山莨菪碱对其作用进行了观察,结果表明,①三组大鼠窒息后软脑膜细静脉血流快相期及血流停止时间均具高度显著性差异(F检验,P<0.01),②三组大鼠窒息后心电消失时间具有高度显著性差异(F检验,P<0.01);③三组大鼠窒息前与窒息后3分钟时血液中Po_2下降值及Pco_2上升值差异具高度显著性(F检验,P均<0.01),血液pH下降具显著性差异(P<0.05);④三组大鼠窒息后3分钟时软脑膜细静脉重度RBC聚集率及白细胞贴壁率具显著性及高度显著性差异(X~2检验,P分别<0.025及0.01)复方丹参及山莨菪碱可增加新生儿窒息时对缺氧的耐受性,可减轻窒息造成的组织、细胞损伤和减少窒息后综合征的发生。
The experiment on asphyxia rats pia mater microcirculation changes and compound Danshen and anisodamine on its role was observed, the results showed that ① three groups of rats after asphyxia the rapid flow of the pial venous blood flow and blood flow stopped time (F test, P <0.01); ② The time of disappearance of ECG after asphyxia in the three groups was highly significant (F test, P <0.01) (P <0.01), and the blood pH decreased significantly (P <0.05). (3) After 3 minutes of asphyxia, the three groups of rats were soft Significant and highly significant differences were found in the rate of RBC accumulation and leukocyte adherent rate between meninges and venules (X ~ 2 test, P <0.025 and 0.01, respectively). Compound Salviae miltiorrhizae and Anisodamine could increase the resistance to hypoxia in neonates with asphyxia By sex, can reduce asphyxia tissue, cell damage and reduce post-suffocation syndrome.