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茜草科植物 Rudgea viburnioides(Ch-am.)Benth 为一种广泛分布于巴西的小树,其叶子及树皮在当地用于治疗消化不良、风湿和梅毒等疾病。以往的文献对此科属植物的化学成分研究无任何报道。作者在化学及生物学方面对该植物进行了一系列研究。作者从其成熟果皮提取物中分离出一种新的三萜化合物 viburgenin(1),经 TLC 检验并与制菌霉素和双氯苯咪唑相比较,此化合物具有一定的抗分支孢子菌类真菌的活性,其结构鉴定为2α,3β,19α,23,24-五羟基-12-烯三萜。同时分离出的还有已知的阿见葡萄糖苷
Ryre family of plants Rudgea viburnioides (Ch-am.) Benth is a small tree widely distributed in Brazil. Its leaves and bark are used locally to treat diseases such as indigestion, rheumatism and syphilis. There is no report on the chemical composition of this genus in previous literature. The author conducted a series of studies on the plant in chemistry and biology. The author isolated a novel triterpene compound viburgenin(1) from its mature peel extract, which was tested by TLC and compared to bacillomycin and bichlorenazole, and the compound has certain resistance to the mycobacterial fungi. The activity of the structure was identified as 2α,3β,19α,23,24-pentahydroxy-12-ene triterpene. At the same time, there is a known arginoside.