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目的分析卡前列素氨丁三醇注射液联合葡萄糖酸钙预防剖宫产后出血的疗效。方法 84例剖宫产后出血患者,随机分为对照组和观察组,每组42例。对照组以缩宫素+米索前列醇治疗,观察组以缩宫素+卡前列素氨丁三醇+葡萄糖酸钙治疗,比较两组治疗效果。结果对照组产后15 min内出血量为(75.71±11.26)ml,产后2 h内出血量为(132.26±12.41)ml,产后24 h内出血量为(287.16±14.17)ml,均多于观察组的(58.14±10.37)、(95.49±11.64)、(145.59±13.75)ml,差异具有统计学意义(P<0.05)。观察组不良反应发生率(14.29%)高于对照组(9.52%),但差异无统计学意义(P>0.05)。结论卡前列素氨丁三醇与葡萄糖酸钙联合可有效预防孕妇剖宫产后出血,且不良反应少,安全性高,可在临床广泛应用。
Objective To analyze the effect of carboprost trometamol injection combined with calcium gluconate in preventing bleeding after cesarean section. Methods 84 cases of postpartum hemorrhage patients were randomly divided into control group and observation group, 42 cases in each group. The control group was treated with oxytocin + misoprostol. The observation group was treated with oxytocin + cardutiloma trometamol + calcium gluconate. The therapeutic effect was compared between the two groups. Results The amount of bleeding within 15 min after birth in the control group was (75.71 ± 11.26) ml, (132.26 ± 12.41) ml within 2 h postpartum and (287.16 ± 14.17) ml within 24 h postpartum, ± 10.37), (95.49 ± 11.64) and (145.59 ± 13.75) ml, respectively. The difference was statistically significant (P <0.05). The incidence of adverse reactions in the observation group (14.29%) was higher than that in the control group (9.52%), but the difference was not statistically significant (P> 0.05). Conclusion The combination of carboprost trometamol and calcium gluconate can effectively prevent cesarean section postpartum hemorrhage in pregnant women with less side effects and high safety. It can be widely used clinically.