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目的:探讨CT灌注成像在脑胶质瘤复发与放射性脑损伤中的鉴别诊断。方法:选取从2009年1月-2010年1月收治的疑为脑胶质瘤术后复发40例,均采取CT灌注成像,测量复发病灶以及放射性坏死病灶CT灌注参数值。结果:本组40例中,脑质瘤复发25例,其中手术病理证实10例,随访证实15例;放射性脑损伤15例,均通过随访证实。在rCBF、rCBV方面,胶质瘤复发组明显高于放射性脑损伤组,P<0.05,有统计学意义。结论:CT灌注成像能将脑肿瘤血流动力学变化反映出来,在胶质瘤复发和放射性坏死的鉴别诊断中有着重要作用。
Objective: To investigate the differential diagnosis of CT perfusion imaging in brain glioma recurrence and radiation brain injury. Methods: From January 2009 to January 2010 admitted to the suspected glioma recurrence in 40 cases were taken CT perfusion imaging, measurement of recurrent lesions and radioactive necrosis CT perfusion parameters. Results: Of the 40 cases, 25 cases of recurrent brain tumor, of which 10 cases were pathologically confirmed, 15 cases were followed up and 15 cases of radiation brain injury were confirmed by follow-up. In rCBF, rCBV, glioma recurrence group was significantly higher than radiation brain injury group, P <0.05, with statistical significance. Conclusion: CT perfusion imaging can reflect the hemodynamic changes of brain tumors and plays an important role in the differential diagnosis of glioma recurrence and radioactive necrosis.