论文部分内容阅读
灌服脂乐50、100、250mg.kg(-1).d(-1)连续四周,能显著降低实验性高脂血症大鼠血清中甘油三脂(TG)和总胆固醇(TC)的水平;显著降低TC/HDL—C比值;同时,能使血浆纤维蛋白元总量降低,也能使血清中LPO和肝组织中LPO降低。结果显示:脂乐胶囊能纠正实验性高脂血症大鼠脂代谢紊乱,增强机体的抗脂质过氧化作用,降低血浆粘滞性,纠正其高凝状态。这些作用均有利于拮抗动脉粥样硬化(AS)的发生和发展。
Oral fat fat 50,100,250 mg. kg (-1). d (-1) for four consecutive weeks could significantly reduce the level of triglyceride (TG) and total cholesterol (TC) in the serum of experimental hyperlipidemic rats and significantly reduce the ratio of TC / HDL-C; at the same time, Lower total fibrin levels can also reduce LPO in serum and LPO in liver tissue. The results showed that Zhile Capsule can correct the disorder of lipid metabolism in experimental hyperlipidemic rats, enhance the body’s anti-lipid peroxidation, reduce the plasma viscosity and correct its hypercoagulable state. These effects are conducive to antagonize the occurrence and development of atherosclerosis (AS).