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巨噬细胞(mφ)的功能与特异性免疫系统的关系,不久前还仅认为是抗体依赖性吞噬作用。自Mosier指出小鼠对羊红细胞的诱导所致的抗体反应需要吸附细胞(adherent cells)以来,现已表明在抗体产生和细胞介导免疫过程中,mφ对各种T细胞亚群的诱导起到必不可少的作用。虽然mφ如抗体依赖性细胞毒作用和淋巴因子激活mφ的其它一些功能也是重要的,而我将讨论并介绍一些主要是我们在研究mφ在诱导和活化T淋巴细胞方面的一些材料。
The relationship between the function of macrophages (mφ) and the specific immune system has only recently been considered as an antibody-dependent phagocytosis. Since Mosier pointed out the need for adherent cells in antibody responses due to the induction of sheep erythrocytes in mice, it has been shown that the induction of various T cell subsets by mφ during antibody production and cell-mediated immunity Essential role. While mφ is also important for other functions such as antibody-dependent cytotoxicity and activation of mφ by lymphokines, and I will discuss and introduce some of the main ones that we are primarily investigating mφ in inducing and activating T lymphocytes.