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目的:动态观察绍兴市区健康体检成人血脂水平的变化,探讨其变化特点及应对措施。方法:以绍兴市区35164名18岁～95岁健康体检者(男性21920例,女性13244例)为调查对象,分4个年龄组(QN、ZN、LQ和LN组)按血脂测定标准化方法测定TC、TG、HDL-C及LDL-C。结果:高TC和高LDL-C居首(2005年36.0%和40.9%,2010年34.1%和24.8%),女性稍高于男性,2010年LDL-C增高有下降趋势(P<0.05),高TG居第2位(2005年27.1%,2010年28.8%);TC、TG及LDL-C变化特点是2005年和2010年有随年龄增加而增高的趋势LQ及LN组明显高于QN、ZN组;女性增高更明显,男性增高有下降趋势,在LN组有明显降低;HDL-C变化是2005年男性仅LN组明显高于其余3组,女性则QN组明显低于其余3组。结论:对社区人群应注意合理膳食、加强锻炼及综合防治的健康教育,必要时服调脂药,是干预血脂增高,降低高血脂危害性的有效途径。
Objective: To dynamically observe the changes of blood lipid levels in adult healthy subjects in Shaoxing city and investigate its changing characteristics and countermeasures. Methods: A total of 35164 health examination subjects (21920 males and 13244 females) aged from 18 to 95 in Shaoxing were enrolled and divided into four groups (QN, ZN, LQ and LN) according to the standardized method TC, TG, HDL-C and LDL-C. Results: High TC and high LDL-C were the highest (36.0% and 40.9% in 2005 and 34.1% in 2010 and 24.8% in 2010). Female patients were slightly higher than males. The increase of LDL-C in 2010 showed a decreasing trend (P <0.05) The TG was the second highest (27.1% in 2005 and 28.8% in 2010). The changes of TC, TG and LDL-C in 2005 and 2010 showed the trend of increasing with age. The LQ and LN groups were significantly higher than QN, ZN group. The increase of female was more obvious. The increase of male decreased and decreased in LN group. The change of HDL-C in 2005 was significantly higher in LN group than in the other three groups and in QN group was significantly lower than that in the other three groups. Conclusion: The community should pay attention to reasonable diet, exercise and comprehensive prevention and control of health education, if necessary, to adjust the lipid-lowering drugs, is an effective intervention to increase blood lipids, reduce the risk of hyperlipidemia.