患者男,65岁。阴囊右侧皮肤红斑、糜烂伴轻度瘙痒和疼痛半年余。曾被误诊为湿疹,治疗无效。皮肤科情况:阴囊右侧见一约3cm×2cm不规则红色斑片,界清,表面轻度糜烂,上覆少许痂皮。皮损组织病理:表皮全层见Paget细胞,真皮浅层有淋巴细胞浸润。诊断:乳房外Paget病。 Male patient, 65 years old. Right scrotum skin erythema, erosion with mild itching and pain more than six months. Had been misdiagnosed as eczema, treatment is invalid. Dermatology: See a right side of the scrotum about 3cm × 2cm irregular red patches, clear, mild erosion on the surface, a little above the crust. Skin lesions histopathology: see the entire layer of Paget cells, superficial dermal lymphocytic infiltration. Diagnosis: Extramammary Paget’s disease.