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目的:观察盐酸川芎嗪在慢性阻塞性肺气肿治疗中的效果。方法:选择在我院呼吸科住院治疗的64例慢性阻塞性肺气肿患者为研究对象,随机分为两组,对照组采用慢性阻塞性肺气肿内科常规治疗,观察组在对照组的基础上加用盐酸川芎嗪治疗,观察两组临床治疗效果及药物的不良反应。结果:对照组总有效率68.75%,观察组总有效率为90.63%,观察组总有效率明显高于对照组,观察组血液流变学及动脉血气的改善亦好于对照组,两组间比较差异显著,具有统计学意义。结论:盐酸川芎嗪对于慢性阻塞性肺气肿具有较好的临床治疗效果,还具有改善血液粘滞度,提高动脉氧分压的作用,并且无明显不良反应,值得在临床上推广使用。
Objective: To observe the effect of ligustrazine hydrochloride in the treatment of chronic obstructive pulmonary emphysema. Methods: Sixty-four patients with chronic obstructive pulmonary emphysema hospitalized in our hospital were selected as study subjects and randomly divided into two groups. Patients in control group were treated routinely with chronic obstructive pulmonary emphysema, and the observation group was basal in control group On the addition of ligustrazine hydrochloride treatment, the two groups observed the clinical effects and adverse drug reactions. Results: The total effective rate of the control group was 68.75%, the total effective rate of the observation group was 90.63%. The total effective rate of the observation group was significantly higher than that of the control group. The improvement of hemorheology and arterial blood gas of the observation group was also better than that of the control group. Significant difference was statistically significant. Conclusion: Tetramethylpyrazine hydrochloride has a good clinical curative effect on chronic obstructive pulmonary emphysema. It also has the effect of improving blood viscosity and increasing arterial oxygen partial pressure, and has no obvious adverse reactions. It is worth to be popularized in clinic.