阿司匹林(ASA)难以降低曾患脑缺血的妇女卒中或死亡的危险,这个问题最早是由加拿大协作研究组织于1978年提出的。该组织的调查结果表明,ASA可使由各种原因所致的男性卒中和死亡危险降低48％,P<0.005。相反,随机接受含有阿司匹林疗法的女性卒中和死亡危险却增加了42%,该结果无统计学差异,P=0.35,但确实未能证明ASA的效果。 Aspirin (ASA) is difficult to reduce the risk of stroke or death in women who have suffered from cerebral ischemia, the first of which was raised by the Collaborative Research Organization of Canada in 1978. The findings of the organization indicate that ASA can reduce the risk of stroke and death from men of any cause by 48%, P <0.005. In contrast, the risk of stroke and death in women randomized to receive aspirin therapy increased by 42% with no significant difference (P = 0.35), but did not demonstrate the efficacy of ASA.