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目的:探讨硝苯地平联合卡托普利治疗原发性高血压病的临床效果。方法:选取2011年6月至2012年5月我院收治的原发性高血压病患者240例进行分析,随机分成A、B、C三组,每组80例,A组采用硝苯地平联合卡托普利治疗,B组采用硝苯地平治疗,C组采用卡托普利治疗,观察三组治疗效果。结果:A组治疗总有效率明显高于B、C组(P<0.05);三组治疗后患者收缩压、舒张压和心率较治疗前均有显著降低(P<0.05),且A组降低水平明显优于B组和C组(P<0.05);三组均无严重不良反应发生。结论:硝苯地平联合卡托普利治疗原发性高血压病能够有效降低患者的血压水平,无不良反应发生,是一种科学有效的治疗方案,值得临床推广。
Objective: To investigate the clinical effect of nifedipine combined with captopril in the treatment of essential hypertension. Methods: From June 2011 to May 2012, 240 patients with primary hypertension admitted to our hospital were randomly divided into three groups (A, B and C), 80 cases in each group. A group was treated with nifedipine Captopril treatment, B group treated with nifedipine, C group treated with captopril, observed the effect of three groups. Results: The total effective rate of group A was significantly higher than that of group B and C (P <0.05). The systolic pressure, diastolic pressure and heart rate of the three groups were significantly lower than those before treatment (P <0.05) The level was significantly better than the B group and C group (P <0.05); no serious adverse reactions occurred in all three groups. Conclusion: Nifedipine combined with captopril treatment of essential hypertension can effectively reduce the patient’s blood pressure levels, no adverse reactions, is a scientific and effective treatment program, worthy of clinical promotion.