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本文报道对15例Sydenham’s舞蹈病患儿采用丙戊酸钠治疗。均系住院病例,以1周上的时间使丙戊酸钠治疗剂量达15～20ms/Kg/天、治疗结束时,再以1周上的时间逐渐停药。本病的诊断标准是排除其他所有可能疾病。全部病例进行常规血液、生化、抗链球菌溶血素“O”(ASO)效价、血清铜、血浆铜兰蛋白,C-反应蛋白浓度、循环免疫复合物、抗核抗体、血清蛋白电泳、血清补体水平,甲状腺功能试验测定及胸部X线和ECG检查。在开始2周观察期中,如效果不佳、则停用该药;如反应不满意,则加用苯巴比妥;早期反应良好者,则持续用药4～8周。治疗达1周时,治疗过程中分别测定血清丙戊
This article reports the use of sodium valproate in 15 patients with Sydenham’s chorea. All were hospitalized cases, to 1 week on the time of sodium valproate treatment dose of 15 ~ 20ms / Kg / day, at the end of treatment, and then gradually stop taking a week on time. The diagnosis of this disease is to exclude all other possible diseases. All cases underwent routine blood, biochemical, anti-streptolysin “O” (ASO) titer, serum copper, cerulein, C-reactive protein concentration, circulating immune complexes, antinuclear antibodies, serum protein electrophoresis, serum Complement level, thyroid function test and chest X-ray and ECG examination. In the first two weeks of observation period, if the effect is not good, then the drug is discontinued; if the reaction is not satisfied, then add phenobarbital; early response is good, then continued medication for 4 to 8 weeks. Treatment up to 1 week, the course of treatment were measured in serum propanil