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目的比较国产与进口试剂在血清学诊断伤寒、副伤寒中的敏感性与特异性 ,为伤寒、副伤寒的诊断提供科学依据。方法对血培养阳性标本及阴性标本的发热病例血清用两种肥达试剂进行抗体检测 ,对其结果进行统计学分析。结果两种试剂对细菌学阳性的血清标本其敏感性有显著性差异 ,国产试剂敏感性高于进口试剂 ,而特异性则无显著性差异 ;用药史对国产与进口试剂检测伤寒结果没有影响 ,对甲型副伤寒检测结果有显著性差异 ;两种试剂对阴性标本的检出结果有显著性差异 ,国产试剂的阳性检出率高于进口试剂。结论按我国现行国标判断标准 ,国产试剂比进口试剂有较高的敏感性和特异性
Objective To compare the sensitivity and specificity of domestic and imported reagents in the serological diagnosis of typhoid and paratyphoid, and provide a scientific basis for the diagnosis of typhoid fever and paratyphoid fever. Methods Serum samples from positive cases of blood culture and negative cases were detected with two kinds of Wada reagent, and the results were statistically analyzed. Results The sensitivity of the two reagents to bacteriologically positive serum samples was significantly different. The sensitivity of domestic reagents was higher than that of imported reagents, but the specificity was not significantly different. The history of drug administration had no effect on the detection of typhoid fever by domestic and imported reagents, Pairs of Paratyphoid A test results were significantly different; two reagents negative samples of the detection results were significantly different, the domestic reagent positive detection rate was higher than imported reagents. Conclusion According to our country’s current national standard judging criteria, domestic reagents have higher sensitivity and specificity than imported reagents