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对226位孕妇在妊娠早期检测hs-CRP并分组,在妊娠24~28周行口服葡萄糖耐量实验(OGTT)进行GDM诊断,对各组数据进行分析、比较。结果:当hs-CRP<0.5 mg/L,0.50~2.10 mg/L,2.11~3.50 mg/L,≥3.51 mg/L,各组相对应的GDM的发病率分别是2%,4%,13%,75%。各组与GDM的OR值及95%CI分别是1.00,1.51(0.88~2.21),4.14(3.56~5.38),12.04(10.76~17.61)。当hs-CRP≥3.51 mg/L,GDM的发病率明显升高。结论:妊娠早期hs-CRP与GDM有关,当hs-CRP明显升高(hs-CRP≥3.51 mg/L)时,GDM发病率明显升高。
226 pregnant women were detected in early pregnancy hs-CRP and grouping, 24-28 weeks gestation oral glucose tolerance test (OGTT) for GDM diagnosis, the data of each group were analyzed and compared. Results: The incidence rates of GDM in each group were 2%, 4% and 13% when the hs-CRP <0.5 mg / L, 0.50-2.10 mg / L, 2.11-3.50 mg / L and ≥3.51 mg / %, 75%. The OR and 95% CI of each group and GDM were 1.00, 1.51 (0.88-2.21), 4.14 (3.56-5.38) and 12.04 (10.76-17.61) respectively. When hs-CRP≥3.51 mg / L, the incidence of GDM increased significantly. Conclusion: The hs-CRP in early pregnancy is related to GDM. The incidence of GDM is obviously increased when hs-CRP is significantly increased (hs-CRP≥3.51 mg / L).