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目的探讨盐酸布替萘芬软膏治疗浅部真菌病的临床疗效。方法使用1%盐酸布替萘芬软膏,早、晚各1次薄薄涂于患处,1～4周判断疗效;并以克霉唑软膏作对照。结果盐酸布替萘芬软膏治疗体股癣痊愈率59.01%,有效率和真菌清除率均95.45%;治疗手足癣痊愈率为44.44%,有效率为92.60%,真菌清除率为88.89%;治疗花斑癣痊愈率为56.25%,有效率为93.75%,真菌清除率93.75%。各病种治疗组与对照组治愈率、有效率及真菌清除率分别比较,差异均有统计学意义(P均<0.05)。结论盐酸布替萘芬软膏治疗浅部真菌病安全、有效。
Objective To investigate the clinical efficacy of butenafine hydrochloride ointment in the treatment of superficial mycosis. Methods 1% butenafine hydrochloride ointment, morning and evening 1 thinly applied to the affected area, 1 to 4 weeks to determine the curative effect; and clotrimazole ointment as a control. Results Budesafion Hydrochloride ointment was 59.01% cure rate of tinea corporis, effective rate and fungal clearance rate were 95.45%; treatment of hand, foot and ringworm cure rate was 44.44%, the effective rate was 92.60%, fungal clearance rate was 88.89%; treatment of flowers Tinea versicolor cure rate was 56.25%, the effective rate was 93.75%, fungal clearance rate of 93.75%. The cure rate, effective rate and fungization rate of treatment group and control group were significantly different (P <0.05). Conclusion Butenafine hydrochloride ointment is safe and effective for the treatment of superficial mycosis.