目的研究分析登革热患者的临床特征以及实验室检测结果,为登革热的早期诊断、治疗提供参考依据。方法回顾性分析本院2014~2016年收治的499例登革热住院患者的病历资料,记录登革热患者的一般临床特征、常规的实验室检查结果和病原学检查结果以及预后,并进行描述性统计分析。结果 499例登革热患者平均年龄为(44.0±18.0)岁,其中22~61岁356例(占71.34%),男性243例(占49%),女性256例(占51%),登革热每年发病高峰期为9~10月。登革热患者主要的临床特征:发热(99.4%)、畏寒/寒战(80.96%)、乏力(96.39%)、头痛(96.99%)、骨骼/肌肉疼痛(96.39%);部分患者出现颜面/胸部潮红(30.86%)、皮疹(24.25%)、结膜充血(5.41%)和眶后痛(5.41%)表现。登革热患者实验室检查结果主要特点:白细胞计数减少(78.2%)、血小板减少(65.5%)、白蛋白降低(50.1%)、丙氨酸氨基转移酶升高(33.9%)、天冬氨酸氨基转移酶升高(64.3%)、乳酸脱氢酶升高(38.7%)、肌酸激酶升高(46.3%)、C反应蛋白升高(44.1%)、血清钾降低(49.7%),但血细胞压积增高比较少见(3.00%)。基础疾病:64例(占12.83%)合并基础疾病,最常见为高血压和2型糖尿病。预后情况:登革热患者平均住院天数为(5.9±2.2)d,平均病程为(9.5±3.0)d。474例(占94.99%)登革热患者经住院治疗后均可痊愈出院。结论登革热每年发病高峰期为9~10月,发病年龄以22~61岁为主,男女比例接近,以发热、畏寒/寒战、乏力、头痛、骨骼/肌肉疼痛为主要临床症状,实验室检查主要表现为白细胞和血小板计数减少、丙氨酸氨基转移酶升高、天冬氨酸氨基转移酶升高、血清钾降低,经过有效治疗后预后良好。 Objective To analyze the clinical characteristics of Dengue fever patients and laboratory test results for the early diagnosis and treatment of dengue fever provide a reference. Methods The clinical data of 499 dengue inpatients admitted from 2014 to 2016 in our hospital were retrospectively analyzed. The general clinical features, routine laboratory and pathological findings, and prognosis of dengue fever patients were recorded. Descriptive statistics were also performed. Results The average age of 499 dengue patients was (44.0 ± 18.0) years old, of which 356 cases (71.34%) were 22 to 61 years old, 243 cases (49%) were male and 256 cases (51%) were female. The peak incidence of dengue Period of 9 to October. The main clinical features of dengue fever were fever (99.4%), chills / chills (80.96%), weakness (96.39%), headache (96.99%) and skeletal / muscular pain (96.39%). Some patients had facial / (30.86%), rash (24.25%), conjunctival hyperemia (5.41%) and orbital pain (5.41%). Laboratory findings of dengue patients Key features: Decreased leukocyte counts (78.2%), thrombocytopenia (65.5%), reduced albumin (50.1%), elevated alanine aminotransferases (33.9%), aspartate amino (64.3%), elevated lactate dehydrogenase (38.7%), creatine kinase increased (46.3%), elevated C-reactive protein (44.1%) and serum potassium decreased (49.7% Increased pressure is relatively rare (3.00%). 64 cases (12.83%) had underlying diseases, the most common being hypertension and type 2 diabetes. Prognosis: The average number of days of hospitalization for dengue fever was (5.9 ± 2.2) days and the average course of disease was (9.5 ± 3.0) days. 474 cases (94.99%) of dengue patients were discharged after hospitalization. Conclusion The peak incidence of dengue fever is from September to October. The age of onset is from 22 to 61 years. The ratio of male to female is close. Fever, chills, chills, fatigue, headache and skeletal / muscular pain are the main clinical symptoms. Laboratory tests Mainly for the white blood cells and platelet count decreased, elevated alanine aminotransferase, aspartate aminotransferase increased serum potassium decreased, after effective treatment of a good prognosis.