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目的 :探讨治疗脑外伤后情感障碍的有效方法。方法 :应用帕罗西汀和阿米替林治疗脑外伤情感障碍患者各 30例 ,治疗组用帕罗西汀 2 0mg/d ,对照组用阿米替林 75mg/d ,均治疗 8周。观察其疗效、不良反应及复发率。结果 :帕罗西汀较阿米替林能显著地改善脑外伤后情感障碍患者的症状 ,且不良反应轻 ,复发率低。结论 :帕罗西汀是治疗脑外伤后情感障碍的有效药物。
Objective: To explore effective methods of treating affective disorder after traumatic brain injury. Methods: Paroxetine and amitriptyline were used in the treatment of 30 patients with brain traumatic affective disorder. The treatment group was treated with Paroxetine 20mg / d, while the control group was treated with amitriptyline 75mg / d for 8 weeks. To observe the efficacy, adverse reactions and recurrence rate. Results: Paroxetine significantly ameliorated the symptoms of patients with mood disorders after traumatic brain injury compared with amitriptyline, with less adverse reactions and lower recurrence rate. Conclusion: Paroxetine is an effective drug for the treatment of post-traumatic brain injury.