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目的观察多巴胺联合酚妥拉明治疗小儿肺炎合并心力衰竭的疗效。方法将2003年1月~2005年12月收治的64例肺炎合并心衰患儿随机分为治疗组32例,对照组32例。两组常规均给予镇静、强心、氧疗、抗感染、止咳平喘、限制入量等治疗。治疗组在常规治疗的基础上同时予小剂量多巴胺5μg/(kg.m in)联合小剂量酚妥拉明5μg/(kg.m in)微量输液器匀速输入。结果治疗组显效20例,有效11例,总有效率96.8%,对照组显效14例,有效8例,总有效率68.7%,两组比较差异有统计学意义(P<0.01),治疗组显著优于对照组。结论对小儿肺炎合并心衰患者采用在常规治疗的基础上加用小剂量多巴胺与酚妥拉明可显著提高疗效,值得临床推广。
Objective To observe the curative effect of dopamine and phentolamine in children with pneumonia complicated with heart failure. Methods 64 cases of pneumonia complicated with heart failure admitted from January 2003 to December 2005 were randomly divided into treatment group (32 cases) and control group (32 cases). Two groups were given routine sedation, cardiac, oxygen therapy, anti-infective, cough and asthma, limiting the amount of treatment. On the basis of routine treatment, the treatment group was given a uniform infusion of small doses of dopamine 5μg / (kg.m in) and a small dose of phentolamine 5μg / (kg.m in). Results There were 20 cases in the treatment group, 11 cases in the treatment group, 96.8% in the control group, 14 cases in the control group, 8 cases in the control group and 68.7% in the control group. The difference between the two groups was statistically significant (P <0.01) Better than the control group. Conclusion The use of small doses of dopamine and phentolamine in patients with pneumonia complicated with heart failure on the basis of routine treatment can significantly improve the efficacy and is worthy of clinical promotion.