腺苷是一种嘌呤核苷,它通过特殊的细胞表面受体诱导哮喘患者支气管狭窄。随种属等的不同,腺苷受体亚型的分布和作用亦不相同。吸入腺苷能刺激多种炎性细胞及炎性介质的释放,但由于其作用机制尚不明确,近年来它作为支气管肺疾病的一种介质,越来越受到人们的关注。 Adenosine is a purine nucleoside that induces bronchoconstriction in asthmatic patients through specific cell surface receptors. Depending on the species and the like, the distribution and effects of adenosine receptor subtypes are also different. Inhalation of adenosine can stimulate the release of a variety of inflammatory cells and inflammatory mediators, but because of its mechanism of action is not clear, in recent years as a bronchial lung disease as a medium, more and more people’s attention.