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1例48岁男性心肌梗死患者因行心肺复苏术后发生谵妄，给予丙泊酚1~2 mg/（kg·h）持续静脉泵入，共21 d。静脉泵入丙泊酚第19天，患者出现高热（体温最高40.0 ℃）、血压下降（最低90/60 mmHg，1 mmHg=0.133 kPa），尿量减少（10 ml/h），尿液呈酱油色。实验室检查示白细胞计数（WBC）17.3×10n 9/L，血红蛋白（Hb）88 g/L，降钙素原（PCT）12.76 μg/L，心肌肌钙蛋白I（cTnI）0.342 μg/L，血肌酐（Scr）239 μmol/L，肌酸激酶（CK）34 667 U/L，肌红蛋白（Myo）58 284 μg/L，乳酸2 mmol/L，真菌（1-3）-β-D-葡聚糖457.9 ng/L；血培养结果示白色念珠菌生长。诊断：丙泊酚输注综合征，脓毒症。立即停止静脉泵入丙泊酚，更换为咪达唑仑注射液（5 mg/h）持续静脉泵入，同时给予抗感染、连续床旁血液滤过等治疗。治疗3 d后，患者体温降至正常；7 d后实验室检查示WBC 5.6×10n 9/L，Hb 95 g/L，PCT 0.12 μg/L，cTnI 0.023 μg/L，CK 43 U/L，Myo 151 μg/L，Scr 78 μmol/L，真菌（1-3）-β-D-葡聚糖88.9 ng/L，尿量90~100 ml/h。n “,”A 48-year-old male patient with myocardial infarction received continuous intravenous pumping of propofol 1-2 mg/(kg· h) for 21 days due to delirium after cardiopulmonary resuscitation. On the 19th day after intravenous pumping of propofol, the patient developed high fever (the highest body temperature was 40.0 ℃), decreased blood pressure (the lowest level was 90/60 mmHg), decreased urine volume (10 ml/h), and dark urine. The laboratory tests showed white blood cell count (WBC) 17.3×10n 9/L, hemoglobin (Hb) 88 g/L, procalcitonin (PCT) 12.76 μg/L, cardiac troponin I (cTnI) 0.342 μg/L, serum creatinine (Scr) 239 μmol/L, creatine kinase (CK) 34 667 U/L, myoglobin (myo) 58 284 μg/L, lactic acid 2 mmol/L, and fungal (1-3)-β-D-glucan 457.9 ng/L. Candida albicans was identified from blood culture. The patient was diagnosed with propofol infusion syndrome and sepsis. Propofol was stopped immediately and replaced by continuous intravenous pumping of midazolam injection (5 mg/h). At the same time, treatments such as anti-infection and continuous bedside hemofiltration were given. After 3 days of treatments, the patient′s temperature dropped to within the normal range. After 7 days of treatments, laboratory tests showed WBC 5.6×10 n 9/L, Hb 95 g/L, PCT 0.12 μg/L, cTnI 0.023 μg/L, CK 43 U/L, myo 151 μg/L, Scr 78 μmol/L, and fungal (1-3)-β-D-glucan 88.9 ng/L. His urine volume was 90-100 ml/h.n