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目的：在中医学藏象理论的指导下，运用系统动力学方法构建胃食管反流病中医系统模型。方法：通过临床研究为模型建立提供资料，运用系统动力学Vensim软件进行模型构建和系统分析。结果：致病因素为输入信息，疾病症状为输出信息，以心、肝、脾、肺、肾五脏子系统为中心，精、气、血、津液为信息媒介，构建了胃食管反流病的中医系统模型。结论：胃食管反流病是一个“以脾为主，五脏一体”的疾病系统。“,”Objective:Under the guidance of visceral state theory of traditional Chinese medicine (TCM),sys-tem dynamics was applied to build a paradigm of TCM for gstroesophageal reflux disease. Methods:Data on gastroesophageal reflux disease was collected,to build a paradigm for gastroesphageal reflux disease with the Vensim software. Result:The pathogenic factors were the input information,symptoms were the output infor-mation. Heart,liver,spleen,lungs and kidneys are the five subsystems as the center,while Qi,blood and body fluid were the medium for information. A paradigm of TCM for gastroesophageal reflux disease was built. Conclusion:Gastroesophageal reflux disease is a disease system in which spleen is the center and five zang organs are integrated.