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目的研究静脉点滴巴曲酶(DF-521)对急性脑血栓患者纤维蛋白溶解系统的影响。方法用美国PacificHemostasis公司提供的D-二聚体测定试剂盒,对43例急性脑血栓患者治疗前后血浆中D-二聚体含量进行了检测并与脑血栓后遗症患者和正常人作对照。结果静点该药后,急性脑血栓患者血浆D-二聚体明显上升。结论DF-521使纤溶系统进一步活跃,加速了溶解血栓的作用
Objective To investigate the effect of intravenous drip batroxobin (DF-521) on fibrinolytic system in patients with acute cerebral thrombosis. Methods Plasma D-dimer levels in 43 patients with acute cerebral thrombosis before and after treatment were measured by D-dimer assay kit supplied by Pacific Hemostasis Company and compared with patients with cerebral thrombosis and normal subjects. Results After intravenous injection of the drug, plasma D-dimer in patients with acute cerebral thrombosis was significantly increased. Conclusion DF-521 further fibrinolytic system accelerated the role of thrombolysis