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一、原发性帕金森病 诊断原发性帕金森病主要依靠临床观察,要考虑以下几点:(1)至少要具备四个典型症状和体征(静止性震颤、少动、僵直和位置性反射障碍)中的二个;(2)是否存在不支持诊断原发性帕金森病的不典型症状和体征例如锥体束征、失用性步态障碍、小脑症状、意向性震颤、凝视麻痹、严重的植物神经功能障碍、明显的痴呆伴有轻度锥体外系症状;(3)脑脊液中高香草酸减少,对确诊早
First, the diagnosis of primary Parkinson’s disease Primary Parkinson’s disease relies mainly on clinical observation, to consider the following points: (1) at least four typical symptoms and signs (rest tremor, infrequent, stiff and positional (2) presence or absence of atypical symptoms and signs that do not support the diagnosis of primary Parkinson’s disease such as pyramidal signs, disabling gait disorders, cerebellar symptoms, intention tremor, gaze paralysis , Severe autonomic dysfunction, and significant dementia associated with mild extrapyramidal symptoms; (3) reduction of vanillic acid in cerebrospinal fluid,