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目的使用国产和进口试剂测定非甲状腺疾病住院患者血清游离三碘甲状腺原氨酸(FT_3)、游离甲状腺素(FT_4)和促甲状腺激素(TSH),探讨该类患者2种试剂检测结果的一致性和典型表现。方法 172例非甲状腺疾病住院患者作为疾病组,120例门诊健康体检人员作为正常对照组,使用国产的安图磁微粒化学发光法试剂和进口的罗氏电化学发光法试剂检测相应样本,进行统计分析。结果疾病组使用国产、进口2种试剂检测,FT_3异常降低率分别为24.4%、20.9%;FT_4异常升高率分别为18.0%、16.9%;TSH异常降低率分别为5.2%、4.1%,异常升高率分别为11.6%、14.5%;2种试剂之间异常发生率差异无统计学意义(P>0.05)。2种试剂检测均表现为疾病组均值相对正常对照组:FT_3偏低、FT_4偏高、TSH偏高。结论非甲状腺疾病住院患者FT_3、FT_4、TSH异常发生率较高,国产的安图试剂和进口的罗氏试剂检测结果一致。
Objective To determine the serum free triiodothyronine (FT_3), free thyroxine (FT_4) and thyrotropin (TSH) in hospitalized patients with non-thyroid disease by using domestic and imported reagents and to investigate the consistency of the results of two reagents in these patients And typical performance. Methods A total of 172 inpatients with non-thyroid disease as the disease group and 120 outpatients as the normal control group were enrolled in this study. The domestic samples of Antu magnetic nanoparticles chemiluminescence reagent and imported Roche electrochemiluminescence reagent were used for statistical analysis . Results The disease group was detected with both domestic and imported reagents. The abnormal rates of FT_3 were 24.4% and 20.9% respectively. The abnormal rates of FT_4 were 18.0% and 16.9% respectively. The rates of abnormalities of TSH were 5.2% and 4.1% respectively. The rates of increase were 11.6% and 14.5% respectively. There was no significant difference between the two reagents (P> 0.05). Two kinds of reagents were detected in the disease group mean normal control group: FT_3 low, high FT_4, TSH high. Conclusion The incidence of FT_3, FT_4 and TSH in hospitalized patients with non-thyroid disease is higher. The results of domestic test and imported Roche reagent are consistent.