1974年约两个月时间内,在印度西部地区发生了一批病例,流行于以玉米为主食的约200个村庄的居民中。发病总数397例,男性患者两倍于女性,死亡106例。临床特征是:经短暂的发热、呕吐和厌食后,出现黄疸。其中部分病例病情轻微而完全愈复,但有些病例于2～3周内迅速出现腹水,继而下肢水肿。有几例还见明显的腹壁侧支循环,有几例肝大。亦有脾大。死亡病例大多先有大量胃肠道出血而突然死 In about two months in 1974, a number of cases occurred in the western part of India and were popularized in about 200 inhabitants of a corn-dominated village. The total incidence of 397 cases, twice as many men than women, 106 cases of death. Clinical features are: jaundice after brief fever, vomiting and anorexia. Some cases of mild and complete recovery, but some cases in 2 to 3 weeks rapidly ascites, followed by lower extremity edema. Several cases also see the obvious abdominal collateral circulation, there are a few cases of liver. There are splenomegaly. Most of the deaths first have a large number of gastrointestinal bleeding and suddenly died